Large-room / whole-floor · Honeywell

Honeywell HPA5300B Air Purifier

Large-room / whole-floor air purifier

Updated October 2026

Quick verdict

A well-matched choice for rooms up to about 2400 square feet.

Strength
Rated for 2400 square feet.
Trade-off
Filters are an ongoing cost.
Right buyer
Rooms up to about 2400 square feet.
Room coverage
2400 square feet
Noise (seller)
55 db
Filter type
HEPA
Product weight
20.5 pounds
Prices change often; the button shows today's price.

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Why it matters

The Honeywell HPA5300B Air Purifier is a large-room / whole-floor air purifier that its maker rates for 2400 square feet.

At the usual 4.8 air changes an hour and an 8-foot ceiling, a 2,400-square-foot rating implies about 1,536 cubic feet of clean air a minute. In a 12-by-15-foot bedroom that would turn the air over roughly 64 times an hour.

Filtration: HEPA. Quietest setting, per the listing: 55 db.

Price-wise it sat in the cheapest third of the 57 large-room / whole-floor models we cover when we checked; the button shows today's price.

It qualifies for our lists Best Air Purifiers for Large Living Rooms, Best Air Purifiers for Home Offices, Best Honeywell filters and air products, where it is ranked against every model that meets the same rule.

Its rated room size of 2,400 square feet is one of the largest ratings we cover: 136 of the 152 purifiers with a stated figure come in lower, and the range runs from 62 square feet to 4,800 square feet.

Compared with the Honeywell QuietClean HFD-010 Air Purifier: rated room size 2400 square feet here vs 62 square feet.

The listing gives a weight of 20.5 pounds.

Who it's for, and who should skip it

Good fit if

  • Rooms up to about 2400 square feet
  • Large open rooms

Look elsewhere if

  • Whole-home filtration on its own
  • Removing gases without a substantial carbon stage

Pros and cons

Pros

  • Rated for 2400 square feet
  • Low setting 55 db

Cons

  • Filters are an ongoing cost
  • Size to the room at 4.8 air changes per hour

Limitations to weigh

  • Specifications are the maker's or seller's own figures; check fit against your equipment's model number and the actual size.

Specifications

The bracket shows where each figure comes from.

Model numberHPA5300BRetailer
Room coverage2400 square feetRetailer
Noise (seller)55 dbRetailer
Filter typeHEPARetailer
Filter classHEPA, Activated CarbonRetailer
Particle size captured0.3 micronRetailer
Product weight20.5 poundsRetailer
Unit count1 CountRetailer

Alternatives worth comparing

More air purifiers we cover

All air purifiers, compared in one table · Every Honeywell product we cover

Final verdict

A well-matched choice for rooms up to about 2400 square feet. Confirm the model it fits before ordering.

Where to buy

Prices change often; the button shows today's price.

Each button opens this exact model. We may earn a commission on tracked links; it never changes what we publish. Disclosure

Questions buyers ask

How big a room does the Honeywell HPA5300B Air Purifier cover?
The maker rates it for 2400 square feet. Treat that as the room size for allergy-level cleaning; larger figures quoted per hour describe one air change, not continuous cleaning.